科研项目
科技部国家重点研发计划项目,可诱导韧带再生的高强度植入物系统的研发(2018YFC1106200),参与,2018.09-2021.06,总经费7246万
科技部国家重点研发计划课题,生物医用防粘连疝气补片开发及应用(2016YFB0303300-03),参与,2016.01-2020.12,总经费1535万
上海市教育委员会科研创新项目,人工血管移植仿真环境构建及细胞黏附研究(ZX201503000017),主持,2015.01-2017.12,8万
国家自然科学基金青年基金,抗血栓及促内皮化混构小口径人造血管研究(51003014),主持,2011.1-2013.12,19万
中国博士后科学基金面上项目,双功能小口径人造血管研究(20100480570),主持,2009.9-2011.8,3万
主持其他项目:
纺织基钨纤维人工胸壁材料研究、面向空降兵高空着陆用非对称结构护踝、水凝胶小口径人工血管材料研究、高顺应性二元小口径人工血管研究、纺织基人工血管材料表面细胞黏附研究、仿真环境下丝涤小口径人造血管与血管内皮细胞相互作用机制研究、具抗凝血及促内皮化双功能小径人造血管的制备等
主持企业委托科技项目:食管支架、面向空降兵的踝护具技术要求及测试、复杂结构网塞刚度评价研究、一次性使用抗菌卫生材料等
参与企业委托科技项目:一体式编织血管覆膜支架、取石网篮等
参与其他项目:诱导软组织再生医用纺织材料
代表性英文论文
1. Chenglong Yu, Guoping Guan*, Stefanie Glas, Lu Wang, Zhutong Li, Lih-Sheng Turng*. A biomimetic basement membrane consisted of hybrid aligned nanofibers and microfibers with immobilized collagen IV and laminin for rapid endothelialization, Bio-Design and Manufacturing, 2021(1), 1-19
2. Chenglong Yu, Meiyi Xing, Lu Wang, Guoping Guan*. Effects of aligned electrospun fibers with different diameters on hemocompatibility, cell behaviors and inflammation in vitro. Biomedical Materials. 2020, 15(3), DOI: 10.1088/1748-605X/ab673c 3.174, II区
3. WU, Jiawei; LIU, Mingjie; wang, Lu; Guan, Guoping*, Influence of Silk Fibroin/Sodium Alginate Coatings on Mineralization of Silk Fibroin Fiber Artificial Ligament Prototypes, Textile Research Journal. 2020, DOI: 10.1177/0040517519898156
4. Yufen WU, Chenglong YU, Meiyi XING, Lu WANG, Guoping GUAN*, Surface modification of polyvinyl alcohol (PVA)/polyacrylamide (PAAm) hydrogels with polydopamine and REDV for improved applicability, Journal of biomedical materials research: Part B. 2020, DOI: 10.1002/jbm.b.34371
5. Xing, meiyi; Yu, Chenglong; Wu, Yufen; wang, Lu; Guan, Guoping*, Preparation and Characterization of PVA/PAAm Hydrogel Vascular Graft Reinforced with Braided Fiber Stent, Textile Research Journal, 2019, DOI: 10.1177/0040517519896753
6. Wen Xue, Seyedmehdi Hossaini Nasr, Guoping Guan*, Liheng Gao, Fan Zhao, Jing Gao, Fujun Wang, Chunqi Qian*, Lu Wang*. An Efficient Surface Modification Strategy Improving Endothelialization with Polydopamine Nanoparticles and REDV Peptides for Stent-Grafts. ACS Applied Bio Materials 2019, 2 (9) , 3820-3827. DOI: 10.1021/acsabm.9b00421.
7. Chonglong YU, Meiyi Xing, Shibo Sun, Guoping Guan*, Lu Wang*. In vitro vascular endothelial cells behaviors on a biomimetic vascular basement membrane. Colloids and Surfaces B: Biointerfaces, 2019, 182 :110381. DOI: 10.1016/j.colsurfb.2019.110381
8. Guoping Guan, Yufen Wu, Chenglong Yu, Xingyou Hu, Meiyi Xing, Wei Wang, Yexiang Wang, Hongjun Wang, Lu Wang*, Hydrogel small diameter vascular graft reinforced with a braided fiber strut for improved mechanical properties, Polymers, 2019, 11, 810; DOI:10.3390/polym11050810
9. Xingyou Hu, Gaotian Shen, Tao Hu, Guoping Guan*, Lu Wang*, Use of an in vitro dynamic culture system to assess flow shear forces upon cell adhesion within different structures, J Chem Technol Biotechnol (2018), DOI:10.1002/jctb.5834
10. Hu X, Hu T, Guan G*, Yu S, Wu Y, Wang L*. 2018. Control of weft yarn or density improves biocompatibility of PET small diameter artificial blood vessels. J Biomed Mater Res Part B 2018:106(3):954–964
第一发明人授权发明专利
1. 一种单纱医用多功能鼻塞及其制备方法,授权时间:2020-08-25 2. 一种非对称结构踝护具个性化快速制备方法,授权时间:2019-09-27 3. 压强可控的人工血管整体水渗透性测试仪及其使用方法,授权时间:2019-09-19 4. 非对称结构踝护具个性化快速制备方法,授权时间:2019-02-26 5. 丝素蛋白纤维规模化生产的全自动脱胶装备及其使用方法,授权时间:2018-12-04 6. 一种测试网塞抗弯刚度的环托法,授权时间:2018-12-04 7. 一种防护踝关节内翻的半刚性踝护具及其制备方法,授权时间:2018-06-22 8. 一种网塞抗压刚度的测试方法,授权时间:2018-05-15 9. 一种脉动式人工血管整体水渗透性测试仪及其使用方法,授权时间:2017-08-01 10. 一种管道器官浇注成型装置及其使用方法,授权时间:2016-11-30 11. 管状纤维集合体增强管道器官浇注成型装置及其使用方法,授权时间:2016-04-06 12. 一种三层机织小口径人造血管及其制备方法,授权时间:2013-06-26 专著及教材 1. 关国平,第2章《医用纺织品的生物学基础》,王璐,Martin W KING主编,《生物医用纺织品》,中国纺织出版社,2011.11,ISBN: 9787506478892 2. Biobased Composites for Medical and Industrial Applications (2/3). in Porous lightweight composites reinforced with fibrous structure. Springer press, 2017. ISBN 978-3-662-53802-9. Yiqi Yang, Jianyong Yu, Helan Xu, Baozhong Sun Editors. 3. 副主编,《生物医用纺织品测试与评价》,王璐 主编,上海:澳洲10计划出版社 4. 《生物医用纺织品设计与制备》,王璐 主编,上海:澳洲10计划出版社